Hi everyone, sharing a simple way I was able to set up ISIS on my mac.
I used a docker file (see below) that I got from a coworker who originally downloaded it from the NEOGeography StereoPipeline Toolkit public github page (although doesn’t look like the docker file still exists there).
You can install the docker file using:
docker build - < asp_isis_320.dockerfile -t asp_isis_320
Then, start up docker using the app on your computer, and run using:
docker run -v $(pwd):/YourDataDir -it ContainerID
Now, you’ll be able to go back to your directory with examples using: cd /YourDataDir
Next, set the data and base paths to the data/kernels you downloaded from ISIS, for example:
export ISIS3DATA=“/YourDataDir/data” (or wherever your data is)
export ISIS3BASE=“/YourDataDir/data/base”
And, now you can run ISIS commands such as (examples for LROC):
lronac2isis from=M101013931RE.IMG to=M101013931RE.cub
spiceinit web=true from=M10103931RE.cub
campt from=M10103931RE.cub LINE=26112 SAMPLE=1266
Hope this is helpful! 
contents of asp_isis_320.dockerfile (since I couldn’t attach a .txt file)
vim: ft=dockerfile:
FROM usgsastro/miniconda3
RUN conda update conda && \
conda install python=3.6 && \
conda config --add channels conda-forge && \
conda config --add channels usgs-astrogeology
RUN conda install -c usgs-astrogeology isis=7.1.0
RUN conda install -c conda-forge rclone
RUN apt-get update &&
apt-get install libgl1 -y &&
rm -rf /var/lib/apt/lists/*
RUN bash -lc ‘python “$CONDA_PREFIX/scripts/isisVarInit.py”’
RUN ln -s /opt/conda/testData /home/working
ENV asp_version=3.2.0
ENV stereo_pipeline=StereoPipeline-3.2.0-2023-01-01-x86_64-Linux
RUN wget https://github.com/NeoGeographyToolkit/StereoPipeline/releases/download/${asp_version}/${stereo_pipeline}.tar.bz2 -O /opt/${stereo_pipeline}.tar.bz2
#RUN wget https://github.com/NeoGeographyToolkit/StereoPipeline/releases/${asp_version}/${stereo_pipeline}.tar.bz2 -O /opt/${stereo_pipeline}.tar.bz2
RUN bzip2 -d /opt/${stereo_pipeline}.tar.bz2
RUN tar -xf /opt/${stereo_pipeline}.tar -C /opt && rm /opt/${stereo_pipeline}.tar
ENV PATH “$PATH:/opt/${stereo_pipeline}/bin”
ENV ISISROOT “/opt/conda”
ENV ISISDATA “/opt/conda/data”
RUN [“apt-get”, “–allow-releaseinfo-change”, “update”]
RUN [“apt-get”, “-y”, “install”, “vim”]
WORKDIR “/home/working”
